A Secret Weapon For Promethazine codeine syrup
A Secret Weapon For Promethazine codeine syrup
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Steer clear of using Promethazine HCl and Codeine Phosphate Oral Alternative in adolescents 12 to eighteen many years of age who produce other possibility things that may increase their sensitivity for the respiratory depressant effects of codeine Unless of course the advantages outweigh the pitfalls.
The respiratory depression involves a discount during the responsiveness of the brain stem respiratory centers to equally increases in carbon dioxide tension and also to electrical stimulation.
Epinephrine – As a result of probable for promethazine to reverse epinephrine's vasopressor outcome, epinephrine really should not be applied to deal with hypotension related to promethazine overdose.
Indicators and signs or symptoms of overdosage with promethazine HCl vary from delicate depression of the central nervous process and cardiovascular process to profound hypotension, respiratory despair, unconsciousness, and unexpected Demise.
Promethazine should not be used by children more youthful than two several years since it might result in major (quite possibly lethal) sluggish/shallow breathing. This issue has transpired Despite having typical doses On this age team.
Though it can help A lot of people, this medication features a hazard for abuse and could from time to time trigger habit. This possibility may very well be increased When you have a substance use problem (for instance overuse of or dependancy to medications/Liquor).
Enhanced tension within your head (increased intracranial strain). Steer clear of the usage of Promethazine Hydrochloride and Codeine Phosphate Oral Remedy In case you have a head injuries or are explained to that you've adjustments while in the tissue of your respective Mind (Mind lesions) or enhanced pressure as part of your head.
Store at place temperature away from light-weight and dampness. Will not retailer in the toilet. Never freeze. Maintain all drugs away from little ones and pets.
Promethazine might reduce seizure threshold. It should be employed with warning in people with seizure Problems or in persons who're employing concomitant medicines, like narcotics or community anesthetics, which can also influence seizure threshold.
It is actually soluble in h2o and freely soluble in Alcoholic beverages. It's a molecular bodyweight of 320.88, a molecular system of C17H20N2S•HCI, and the next structural formulation:
It really is soluble in water and freely soluble in Alcoholic beverages. The molecular weight is 320.88. Its molecular system is C17H20N2S•HCl, and it's got the following chemical composition.
To scale back the potential risk of dizziness and lightheadedness, get up little by little when growing from a sitting down or lying situation.
Codeine has great antitussive activity, although less than that of morphine at equivalent doses. It can be Utilized in choice to morphine, simply because Negative effects are infrequent at the standard antitussive dose of codeine.
The treatment of overdosage with promethazine and codeine is basically symptomatic and supportive. Only in circumstances of extreme overdosage or person sensitivity do vital signs which includes respiration, pulse, hypertension, temperature, and EKG have to be monitored. Activated charcoal orally or by lavage might be given, or sodium or magnesium sulfate orally as being a cathartic. Notice must be presented to the reestablishment of ample respiratory exchange as a result of provision of the patent Promethazine codeine syrup airway and institution of assisted or managed air flow.